She filed Wednesday morning in Los Angeles Superior Court.
In the filing, she requested that her name be restored from Parker's name to Eva Jacqueline Longoria.
Documents also state that the couple had a prenuptial agreement. It was signed in 2007, the year they wed, and amended in 2009.
She is seeking spousal support.
She cited irreconcilable differences for the split.
The filing comes on the heels of the latest Us Weekly, which reports that Longoria Parker, 35, recently discovered that her husband, 28, has been exchanging personal texts with a mutual female friend for nearly a year -- hundreds in just one month.
"Eva is heartbroken by the betrayal," says one insider (Longoria Parker’s rep had no comment; Parker’s rep could not be reached).
The two met in November 2004.
They had a brief rough patch that year -- "We were going through growing pains," she explained to Cosmopolitan -- but they worked it out.
He popped the question in 2006. "It was more than I'd imagined," she told Cosmo of his proposal. "I was shocked, too. It was like two in the morning. He got down on one knee. He was so nervous, which is what I find so surprising and sweet. I said, 'Honey, you know how much I want to marry you!'"
They famously wed in a $1.5 million wedding at a 17th century castle in Paris in July 2007 -- in front of her Desperate Housewives co-stars, including Teri Hatcher and Felicity Huffman.
Baby rumors soon followed.
"Tony and I want ... as many as we can have. Three, four, five," she said in 2008. "We think about adopting too."
The same year, the 5-foot-2 star dodged pregnancy rumors when she packed on 7 lbs. for Housewives ("I'm just fat," she quipped).
The two appeared to be in fine shape this past summer as they celebrated his birthday and their third wedding anniversary.
"We're thinking about it. Pretty soon," he told Us in June when asked about starting a family. "She's got one more year with Desperate Housewives, so we'll see what happens."
With their time apart, he told Us, "Skype helps a lot. As long as you both make an effort, it works ... [but I miss] not being able to kiss her every day!"